p-Methoxy-trans-cinnamic acid
4-METHOXYCINNAMIC ACID
CAS: 943-89-5
Molecular Formula: C10H10O3
p-Methoxy-trans-cinnamic acid - Names and Identifiers
| Name | 4-METHOXYCINNAMIC ACID |
| Synonyms | 4-METHOXYCINNAMIC ACID 4-Methoxycinnamic acid (E)-4-Methoxycinnamic acid trans-4-MethoxyClnnamic acid p-Methoxy-trans-cinnamic acid 4-Methoxy-trans-cinnamic acid |
| CAS | 943-89-5 |
| EINECS | 213-405-4 |
| InChIKey | AFDXODALSZRGIH-QPJJXVBHSA-N |
p-Methoxy-trans-cinnamic acid - Physico-chemical Properties
| Molecular Formula | C10H10O3 |
| Molar Mass | 178.18 |
| Density | 1.195±0.06 g/cm3(Predicted) |
| Melting Point | 173.5 °C(lit.) |
| Boling Point | 342.6±17.0 °C(Predicted) |
| pKa | 4.60±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| MDL | MFCD00004398 |
p-Methoxy-trans-cinnamic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| RTECS | UD3391300 |
| FLUKA BRAND F CODES | 8 |
| TSCA | Yes |
| Hazard Class | IRRITANT |
p-Methoxy-trans-cinnamic acid - Upstream Downstream Industry
p-Methoxy-trans-cinnamic acid - Reference
| Reference Show more | 1. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 |
p-Methoxy-trans-cinnamic acid - Nature
| solubility | Soluble in ethanol, ethyl acetate and other organic solvents. |
| BRN | 510468 |
| NIST chemical information | 2-Propenoic acid, 3-(4-methoxyphenyl)-, (e)-(943-89-5) |
| EPA chemical information | 2-Propenoic acid, 3-(4-methoxyphenyl)-, (2E)- (943-89-5) |
Last Update：2024-04-09 20:52:54
p-Methoxy-trans-cinnamic acid - Uses and synthesis methods
p-methoxycinnamic acid sunscreen
At present, the most commonly used p-methoxycinnamic acid sunscreen agent is p-methoxycinnamate octyl, which is a colorless or light yellow liquid, insoluble in water, soluble in organic solvents such as ethanol and ethyl acetate, It has no irritation to the skin, has high safety in use, and has high ultraviolet absorption rate for UVB area, can effectively prevent 280-330mm ultraviolet rays, and has high absorption rate. It is; it can effectively prevent skin redness and sunburn. At present, this raw material is widely used in many sunscreen cosmetics in various countries. It is obtained by the reaction of p-methoxybenzaldehyde and malonic acid.
Preparation method
p-methoxybenzaldehyde was used as raw material, ammonium acetate was used as catalyst, microwave radiation technology was used, and p-methoxycinnamic acid was synthesized under solvent-free conditions through verta reaction.
biological activity
(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) can be separated from Arachis hypogaea,Scrophularia buergeriana Miquel,Aquilegia vulgaris,Anigozanthos preissii, etc. (E)-3-(4-Methoxyphenyl)acrylic acid has significant liver protective activity, anti-amnesia, enhancing cognitive activity, lowering blood sugar and neuroprotective activity.
Last Update：2024-04-09 01:59:50
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View History
p-Methoxy-trans-cinnamic acid
螺[异苯并呋喃-1(3H),4'-哌啶]-3-酮
2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
1,3-环己烷二胺 (顺反混合物)
(3S,4S)-叔-丁基 4-甲基吡咯烷-3-甲酸基酯
2-{[2-(4-氯苯基)喹啉-4-基]甲酰胺}乙酸
2-[(2-氰基乙酰基)氨基]-5-苯基-噻吩-3-羧酸甲酯
盐酸-4-氨基-5-咪唑碳酰胺
四甲基三乙酰氧基硼氢化铵
氨氯地平比索洛尔加成杂质1
螺[异苯并呋喃-1(3H),4'-哌啶]-3-酮
2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
1,3-环己烷二胺 (顺反混合物)
(3S,4S)-叔-丁基 4-甲基吡咯烷-3-甲酸基酯
2-{[2-(4-氯苯基)喹啉-4-基]甲酰胺}乙酸
2-[(2-氰基乙酰基)氨基]-5-苯基-噻吩-3-羧酸甲酯
盐酸-4-氨基-5-咪唑碳酰胺
四甲基三乙酰氧基硼氢化铵
氨氯地平比索洛尔加成杂质1
Raw Materials for p-Methoxy-trans-cinnamic acid
Downstream Products for p-Methoxy-trans-cinnamic acid